Personality explains the relationship between psychedelic use and depression; a comparison study with non psychedelic users

A new study explores that relationship between psychedelic use and depression. This cross-sectional study (n=400 psychedelic users, matched with non-users) examines the mental health and personality characteristics of Swedish individuals with psychedelic experiences. Results indicate that psychedelic users exhibit lower depression levels (PHQ-9) and higher drug use (DUDIT), with openness (Big Five) being notably different (d=1.72), contributing to the observed effects on depression. The findings suggest potential implications for understanding and approaching psychedelic users in the context of mental health and personality traits.

Abstract

“Interest in psychedelics is increasing due to potential for improved mental health and quality of life. However, adverse effects on mental health are still a concern. Personality traits have been suggested to both influence the psychedelic experience and mental health, and even be changed by psychedelic use. The present study describes for the first time a national sample of Swedish psychedelic users (n = 400) compared to a sex and age-matched sample of non-users (n = 400) regarding mental health variables (depression, insomnia, problematic alcohol and drug use, and dissociation) and personality (Big Five). Data was collected in an online survey including individuals from 16 years of age who had at least one psychedelic experience. The main results reported psychedelic users as less depressed (Patient Health Questionnaire-9; PHQ-9) (d = -0.29) and having more use of drugs (Drug Use Disorders Identification Test; DUDIT) (d = 1.27). In the Big Five personality traits, openness differed notably (d = 1.72), and the between-group effects in PHQ-9 were explained by lower neuroticism. In summary, psychedelic users report less depression and higher drug use, and this is partly due to personality traits. These results could have implications on how we view psychedelic users and the use of psychedelic drugs.”

For more psychedelic news and research, visit the psychedelic health professional network homepage.

Previous
Previous

Microdosing psychedelics and the risk of cardiac fibrosis and valvulopathy: Comparison to known cardiotoxins

Next
Next

Self-experience in MDMA assisted therapy of PTSD