Psilocybin for Creativity: An Investigation

This double-blind, placebo-controlled, parallel-group study investigated the merits of psilocybin for creativity.

They found that psilocybin induces a time- and construct-related differentiation of effects on creative thinking, suggesting that psychedelics could be a novel tool to investigate underlying neural mechanisms of the creative process. Additionally, these findings add some support to the historical claims that psychedelics can influence aspects of the creative process, reducing conventional, logical thinking, and giving rise to novel thoughts. However, the findings emphasize the distinction between spontaneous and deliberate creative cognition, as well as acute and persisting effects of the drug.

ABSTRACT

Creativity is an essential cognitive ability linked to all areas of our everyday functioning. Thus, finding a way to enhance it is of broad interest. A large number of anecdotal reports suggest that the consumption of psychedelic drugs can enhance creative thinking; however, scientific evidence is lacking. Following a double-blind, placebo-controlled, parallel-group design, we demonstrated that psilocybin (0.17 mg/kg) induced a time- and construct-related differentiation of effects on creative thinking. Acutely, psilocybin increased ratings of (spontaneous) creative insights, while decreasing (deliberate) task-based creativity. Seven days after psilocybin, number of novel ideas increased. Furthermore, we utilized an ultrahigh field multimodal brain imaging approach, and found that acute and persisting effects were predicted by within- and between-network connectivity of the default mode network. Findings add some support to historical claims that psychedelics can influence aspects of the creative process, potentially indicating them as a tool to investigate creativity and subsequent underlying neural mechanisms.

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