UP-TO-DATE, RESEARCH BASED INFORMATION ABOUT PSYCHEDELICS.
Esketamine nasal spray versus quetiapine for treatment-resistant depression
In patients with treatment-resistant depression, esketamine nasal spray plus an SSRI or SNRI was superior to extended-release quetiapine plus an SSRI or SNRI with respect to remission at week 8.
Comparing neural correlates of consciousness: from psychedelics to hypnosis and meditation
Overall, these results extend our understanding of the mechanisms of action of ASC and highlight the importance of exploring how these effects can be leveraged in the treatment of psychiatric disorders.
Comparative acute effects of mescaline, lysergic acid diethylamide, and psilocybin in a randomized, double-blind, placebo-controlled cross-over study in healthy participants
The results indicate that any differences in the pharmacological profiles of mescaline, LSD, and psilocybin do not translate into relevant differences in the subjective experience.
Ketamine versus ECT for nonpsychotic treatment-resistant major depression
Ketamine was noninferior to ECT as therapy for treatment-resistant major depression without psychosis.
ECT vs ketamine for major depressive disorder: New data
This supports a recommendation for a trial of ketamine before a trial of ECT for patients with MDE, though this recommendation is limited by the small size and number of existing trials
Direct comparison of the acute effects of lysergic acid diethylamide and psilocybin in a double-blind placebo-controlled study in healthy subjects
Both doses of LSD and the high dose of psilocybin produced qualitatively and quantitatively very similar subjective effects.
Ketamine vs ECT for depression: First head-to-head results
Symptom reduction following ketamine infusions in severely ill patients suggest that ketamine, despite being inferior to ECT, can be a safe and valuable tool .