Overall, our findings indicate reliable variation across psychedelic substances’ propensities to affect vision and in their qualitative effects on visual perception.

These results provide empirical groundwork for developing effective evidence-based meditation protocols for psychedelic preparation. They also highlight the importance of considering psychedelic users’ level of previous meditation experience in optimising such interventions.

Safrole is found in the sassafras tree and many other plant species that grow abundantly around the world. So if someone with enough capital and ingenuity felt up to the task, they could work with (and around) existing laws to figure out a way to make MDMA from plants.

There is a push to shrink the anticipated 17-year research-to-practice gap for psychedelic-assisted therapy (PAT), offering precarious hope to those with disabling mental health conditions.

Anyone hoping the psychedelic community would come together in cosmic oneness after the Great Lykos Schism of 2024 may be disappointed, as the confirmation of Robert F Kennedy Junior as Secretary of Health and Human Services last week provoked starkly-polarised reactions from the field.

Perceptions of health outcomes following psychedelic use were broadly positive, and psilocybin was reported to be the most effective substance for both physical and mental health symptoms.

We asked Tommaso why he’s so excited about short-acting psychedelics (5-MeO-DMT), how his research into psychedelics and sexual function took off, and what open questions he’d most like to study next.

A first-ever clinical trial of MDMA-assisted therapy for active-duty service members with PTSD.

This revealed that participants consuming psychedelics for spiritual or self-healing purposes reported more intense, while those motivated by curiosity reported less intense ego dissolution experiences.