Classic psychedelic experiences may exert a positive effect on the cultivation and maintenance of health-related behaviors such as regular meditation practice.

Psychedelic drugs have good safety profiles, but a recent systematic review concluded that adverse events in psychedelic trials are poorly defined and not systematically assessed.

These results extend the primary findings from the largest randomised clinical trial of psilocybin for TRD to examine other outcomes that are of importance to patients.

the acute and persisting clinical improvements observed following psilocybin support further study of its potential in the treatment of major depression.

Ibogaine is a powerful psychoactive substance that not only alters perception, mood and affect, but also stops addictive behaviors.

“Those meetings are beautiful,” he says. “They’ve given me a real appreciation of how empowering it is for a cancer patient to help other cancer patients.”

Requiring trainees to take psychedelic drugs does not seem ethically legitimate.

Although the results are promising, future trials are needed to assess the optimal psychedelic, dose, number of sessions required.

Classical psychedelic users showed greater psychological strengths and well-being, and lower levels of distress.

We hope for this article to support clinical research on PAGP by presenting a therapeutic framework and outlining its mechanisms and challenges.

The identified studies suggest that mystical-type experiences under psychedelics are associated with improvements in some areas of well-being.