UP-TO-DATE, RESEARCH BASED INFORMATION ABOUT PSYCHEDELICS.
Treating posttraumatic stress disorder and alcohol use disorder comorbidity: Current pharmacological therapies and the future of MDMA-integrated psychotherapy
The following reviews the current research for clinical pharmacotherapies, as well as MDMA-integrative psychotherapy as they pertain to PTSD and AUD in isolation and co-occurrence. Future directions for the role of psychedelic-integrative therapy for the treatment of this comorbidity are discussed.
Reports of self-compassion and affect regulation in psilocybin-assisted therapy for alcohol use disorder: An interpretive phenomenological analysis
Our results support the assertion that psilocybin increases the malleability of self-related processing, and diminishes shame-based and self-critical thought patterns while improving affect regulation and reducing alcohol cravings. These findings suggest that psychosocial treatments that integrate self-compassion training with psychedelic therapy may serve as a useful tool for enhancing psychological outcomes in the treatment of AUD.
Perspectives on the therapeutic potential of MDMA: A nation-wide exploratory survey among substance users
Overall, a majority of individuals reported a willingness to try MDMA-assisted therapy if it were determined to be an appropriate treatment for them (58.8%).
Could ketamine-assisted therapy help treat alcohol disorder?
A new £2.4 million phase III trial delivered through seven NHS sites across the UK will investigate whether ketamine-assisted therapy could help treat alcohol disorder.
Psychedelic Alpha Bulletin – A deep dive into psilocybin for alcohol use disorder
Heavy drinking days decreased by about 80% among those in the psilocybin group.
Classic psychedelics and alcohol use disorders: A systematic review of human and animal studies
After selection, 27 studies were included. Human studies (n = 20) generally show promising data and seem to indicate that classic psychedelics could help reduce alcohol consumption.
Percentage of heavy drinking days following psilocybin-assisted psychotherapy vs placebo in the treatment of adult patients with alcohol use disorder: A randomized clinical trial
Psilocybin administered in combination with psychotherapy produced robust decreases in percentage of heavy drinking days.
The effects of MDMA-assisted therapy on alcohol and substance use in a phase 3 trial for treatment of severe PTSD
MDMA-AT for severe PTSD may also lead to subclinical improvements in alcohol use.
Adjunctive ketamine with relapse prevention–based psychological therapy in the treatment of alcohol use disorder
Ketamine treatment was well tolerated and was also helpful.
Psychedelic treatment for co-occurring alcohol misuse and post-traumatic stress symptoms among United States Special Operations Forces Veterans
The current study examined the correlations between psychedelic treatment (ibogaine & 5-MeO-DMT) and changes in alcohol misuse among trauma exposed United States SOFV.
Mystical-type experiences occasioned by ketamine mediate its impact on at-risk drinking: Results from a randomized, controlled trial.
Mystical-type experiences occasioned by ketamine mediate its impact on at-risk drinking
First study of safety and tolerability of 3,4-methylenedioxymethamphetamine-assisted psychotherapy in patients with alcohol use disorder.
MDMA-assisted psychotherapy for alcohol use disorder