
UP-TO-DATE, RESEARCH BASED INFORMATION ABOUT PSYCHEDELICS.
Interactions between classic psychedelics and serotonergic antidepressants: Effects on the acute psychedelic subjective experience, well-being and depressive symptoms from a prospective survey study
Individuals presumed to be on serotonergic antidepressants during psychedelic use display reduced subjective effects but similar antidepressant effects compared to those not undergoing SRI treatment. Further controlled research is needed to comprehend the interplay between serotonergic antidepressants and psychedelics, illuminating potential therapeutic benefits and limitations in clinical contexts.
Trip-killers: a concerning practice associated with psychedelic drug use
We recommend that emergency physicians ask patients about trip-killers if psychedelic drug use is suspected. This conversation should occur promptly on arrival to hospital, and before any benzodiazepines or antipsychotics are prescribed
Drug-drug interactions between classic psychedelics and psychoactive drugs: a systematic review
These studies provide insights into the interactions between classic psychedelics and a range of drugs, including antidepressants, antipsychotics, anxiolytics, mood stabilisers, recreational drugs and others.
Serotonergic antidepressant use is associated with weaker psilocybin effects
Serotonergic antidepressants appear to weaken psilocybin’s effects relative to a nonserotonergic antidepressant.
Effects of selective serotonin reuptake inhibitor use on 3,4-methylenedioxymethamphetamine–assisted therapy for posttraumatic stress disorder: A review of the evidence, neurobiological plausibility, and clinical significance
There is strong neurobiological plausibility for the hypothesis that chronic SSRI use dampens response to MDMA-assisted therapy.
Drug-drug interactions between psychiatric medications and MDMA or psilocybin: a systematic review
This systematic review offers a compilation of existing research on psychiatric drug-drug interactions with MDMA or psilocybin.
Psychedelics & SSRI antidepressants: overlaps, interactions & safety
here we present the top ten available articles exploring psychedelics, serotonin and SSRIs