Unlocking the self: Can microdosing psychedelics make one feel more authentic?

The abstract of this intriguing little exploratory study reads: "Background and aim: In the present study, we focus on the relationship between state authenticity – the experience of being true to oneself in a particular moment – and microdosing – a practice that implies repeatedly ingesting very small doses of psychedelics that do not reach the threshold for perceptual alterations. We propose that microdosing could increase state authenticity through influencing people's mood and the number and satisfaction with daily activities. Methods: We used self-assessments of state authenticity collected from 18 microdosers in the Netherlands across the period of 1 month for a total of 192 observations. Results: We found that on the microdosing day and the day thereafter, state authenticity was significantly higher. Furthermore, the number of activities and the satisfaction with them were higher on the day when participants microdosed, while the following day only the number of activities was higher. Both the number or activities and the satisfaction with them were positively related to state authenticity. Conclusion: We propose that feeling and behaving authentically could have a central role in explaining the positive effects of microdosing on health and wellbeing that are reported by current research."

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Chronic MDMA use is related to glutamate and GABA concentrations in the striatum, but not in the anterior cingulate cortex

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In naturalistic psychedelic use, group use is common and acceptable